Abstract #1543

Noise Considerations for a Microsolenoid at 15.2T Designed for MR Microscopy

Benjamin M Hardy^1,2, Yue Zhu^1,3, Mark D Does^1,4,5, Adam W Anderson^1,3,4, and John C Gore^1,2,3,4

¹Vanderbilt University Institute of Imaging Science, Vanderbilt University, Nashville, TN, United States, ²Department of Physics and Astronomy, Vanderbilt University, Nashville, TN, United States, ³Department of Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, TN, United States, ⁴Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, United States, ⁵Department of Radiology and Radiological Science, Vanderbilt University Medical Center, Nashville, TN, United States

Synopsis

Magnetic Resonance Microscopy aims to produce micron scale resolution images in reasonable times, but SNR decreases as voxel sizes shrink. RF coils must be optimized and their performance depends on coil resistance and sample size. We compared the relative performance of a commercially available cryogenically cooled surface coil of 24 mm in diameter to a smaller, 1.5 mm diameter, room temperature microcoil at 15.2T. A silver microsolenoid had threefold SNR increase but with decreased FOV and susceptibility artifacts. An optimized microcoil should be able to produce images with 10 µm isotropic resolution within 10 hours with an SNR of 10.

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