Contrast-free 3D Cartesian MRA of the thoracic aorta in 3 min: preliminary clinical evaluation
Anastasia Fotaki1, Camila Munoz1, Alina Hua1, Yaso Emmanuel2, Karl Philip Kunze1,3, Radhouene Neji1,4, Pier Giorgio Masci1, René Botnar1,5, and Claudia Prieto1,5
11School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom, 2Guy's and St Thomas' Hospital, London, United Kingdom, 3MR Research Collaborations, Siemens Healthcare Limited, Frimley, United Kingdom, 42MR Research Collaborations, Siemens Healthcare Limited, Frimley, United Kingdom, 5Escuela de Ingeniería, Pontificia Universidad Católica de Chile, Santiago, Chile
Cardiovascular Magnetic Resonance Angiography is established for serial monitoring of thoracic aortic disease. Limitations of the current approach include the diaphragmatic navigation, leading to long acquisition times and the correction of the aortic motion, solely in one direction. We propose a T2-prep bSSFP sequence that incorporates image-based navigation and inline non-rigid motion-correction for efficient, free-breathing and isotropic aortic imaging. Comparison between the conventional and the research sequence shows similar diagnostic confidence with both techniques in much shorter acquisition time [3.11.1min (iNAV) versus 11.5 min3.4 (dNAV),P<0.0001] and good agreement of aortic measurements between both techniques, holding promise for forthcoming clinical adoption.
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