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Abstract #1559

Comparison of Interpolation Methods for Ex-vivo and In-vivo Cardiac Diffusion Tensor Imaging

Johanna Stimm1, Sebastian Kozerke1, and Christian Stoeck1,2
1Institute for Biomedical Engineering, University and ETH Zurich, Zuerich, Switzerland, 2Division of Surgical Research, University Hospital Zurich, University Zurich, Zurich, Switzerland


To address the challenge of low resolution and limited number of slices in in-vivo cDTI, and the need for 3D structural information in image-based modeling, we compare five interpolation techniques of predominant cardiomyocyte orientation: two low-rank models, one rule-based method and two tensor interpolation approaches. The direct tensor interpolation approaches result in the smallest errors, followed by the low-rank models and the rule-based method. In view of an optimal experimental design in-vivo, the ex-vivo experiments suggest a larger benefit of increasing in-plane resolution rather than SNR, and a non-linear increase in error for less than five short-axis slices.

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