Non-selective refocusing pulse optimization for T2-prep in free-breathing 3D CMRA at 7T with single-transmit coil
Shubhajit Paul1, Raphael Tomi-Tricot1,2, Karl Philipp Kunze1,2, Shaihan Malik1,3, Joseph V. Hajnal1,3, Philippa Bridgen1,3, Thomas Wilkinson1,3, Sharon Giles1,3, Radhouene Neji1,2, Reza Razavi1, Claudia Prieto1,4, and René Michael Botnar1,4
1School of Biomedical Engineering and Imaging Sciences, King’s College London, London, United Kingdom, 2MR Research Collaborations, Siemens Healthcare Limited, Frimley, United Kingdom, 3The London Collaborative Ultra high field System (LoCUS), London, United Kingdom, 4Escuela de Ingeniería, Pontificia Universidad Católica de Chile, Santiago, Chile
In spite of the promised increase in signal-to-noise ratio and contrast to noise ratio, 3D whole-heart imaging at 7T remains challenging predominantly due to B1, B0 inhomogeneity, specific absorption rate limitations and coil-depth issues for single transmit. Here, we developed a toolbox to optimize the adiabatic hyperbolic secant refocusing pulse with respect to B1 and B0 inhomogeneity typically used for T2-preparation in non-contrast 3D Coronary Magnetic Resonance Angiography (CMRA). We present phantom and in vivo data for 3D CMRA employing a low excitation flip-angle scheme.
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