Meeting Banner
Abstract #1572

Preliminary Clinical Validation of Non-rigid Motion-compensated 3D Whole-heart T2 mapping in a hybrid PET-MR system

Alina Schneider1, Camila Munoz1, Alina Hua1, Karl P Kunze1,2, Radhouene Neji1,2, Tevfik F Ismail1, René M Botnar1, and Claudia Prieto1
1School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom, 2MR Research Collaborations, Siemens Healthcare Limited, Frimley, United Kingdom


Simultaneous 18F-FDG PET-MRI has shown promise for improved diagnostic accuracy of inflammatory cardiac diseases. However, respiratory motion and mis-registration between free-breathing 3D PET and 2D breath-held MR images remain challenges that have hindered its clinical adoption. We have recently proposed a free-breathing non-rigid motion-compensated 3D whole-heart T2-mapping that enables detection of myocardial inflammation and provides non-rigid respiratory motion fields to correct simultaneously acquired PET data in a 3T PET-MR system. Here, we perform a preliminary clinical validation of this approach in 8 patients with suspected cardiovascular disease. Good image quality with T2 values comparable to clinical 2D T2-mapping was achieved.

This abstract and the presentation materials are available to members only; a login is required.

Join Here