By exploiting the field-dependent anisotropy of collagen, valuable clinical information can be obtained, such as fibre tractography. We investigated the use of a priori anatomical knowledge such as scout scan, using both simulations and experimentally acquired images. We conclude that only 3 scanning directions may be sufficient for robust analysis, instead of 9 or more in the case when no such information is used. The method is also compatible with low SNR values associated with low-field MRI.
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