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Abstract #1695

Proton magnetic resonance spectroscopy of the distal metacarpus/tarsus in Thoroughbred racehorses with and without catastrophic fractures.

Charlotte L Hewitt-Dedman1, Sarah E Taylor1, Tobias Schwarz1, Carola R Daniel1, Maria Chiara Pressanto1, and Lucy E Kershaw2
1Royal Dick School of Veterinary Studies and Roslin Institute, Royal Dick School of Veterinary Studies and Roslin Institute, University of Edinburgh, Edinburgh, United Kingdom, 2BHF Centre for Cardiovascular Science and Edinburgh Imaging, BHF Centre for Cardiovascular Science and Edinburgh Imaging, University of Edinburgh, Edinburgh, United Kingdom

Synopsis

Fractures of the third metacarpal/tarsal bone are common in racehorses. Racehorse cadaver limbs underwent single voxel magnetic resonance spectroscopy (MRS) and computed tomography. The percentage fat content (FC) and the mean bone mineral density (BMD) was calculated at 3 locations within the bone. A significant negative correlation was identified for mean BMD and percentage FC for all condyles and in bone marrow of the third metacarpal/tarsal distal diaphysis. The median percentage FC was lower in horses with fractures compared to controls. These findings suggest that fat and bone are capable of mutual regulation in Thoroughbred racehorses.

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