Abstract #1719
Comparison between IVIM-DKI, MRE and DCE-Tofts quantitative techniques at 3.0 T multiparametric prostate protocol
Trinidad González Padin1,2, Nicolas Moyano Brandi1,2, María Paula Del Pópolo1,2, Natalia Noemi Massaccesi Bove1,2, Clara Chacon1,2, Federico Julian Gonzalez1,3,4, Roberto Andrés Isoardi1,3,4,5, Pedro Pablo Ariza1,2, Andrés Dominguez1, Eduardo H,M.S.G de Figuereido6, and Daniel Fino Villamil1,2,4,5
1MRI department, Fundación Escuela de Medicina Nuclear, Mendoza, Argentina, 2MRI department, Fundación Argentina para el Desarrollo en Salud, Mendoza, Argentina, 3GQNYCS, Comisión Nacional de Energía Atómica, Buenos Aires, Argentina, 4Instituto Balseiro, Universidad Nacional de Cuyo, San Carlos de Bariloche, Argentina, 5FCEN, Universidad Nacional De Cuyo, Mendoza, Argentina, 6General Electric- Healthcare, Sao Paulo-SP, Brazil, Brazil
Synopsis
Since there is no clear relationship between the coefficients of the DWI biexponential model and permeability and pharmacokinetics, we aim to correlate the coefficients associated to the IVIM-DKI model, MRE, and quantitative and semiquantitative maps of the multiparametric prostate protocol. Through a Python algorithm, the DWI data acquisition was fitted to an IVIM-DKI function after a semi-automatic segmentation. Then, PR, PCa and healthy tissue were evaluated, and the IVIM-DKI parametric maps were contrasted with the DCE and MRE through a Pearson’s correlation test. Empirical relationships were established between the pseudo-perfusion models, semiquantitative maps and the variables of the compartmental models.
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