Sensitivity comparison of probabilistic and deterministic DTI tractography for robust characterization of arm skeletal muscle geometry
Divya Joshi1,2, Julius PA Dewald1,2,3, and Carson Ingo2,4
1Department of Biomedical Engineering, Northwestern University, Chicago, IL, United States, 2Department of Physical Therapy and Human Movement Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL, United States, 3Department of Physical Medicine and Rehabilitation, Northwestern University Feinberg School of Medicine, Chicago, IL, United States, 4Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL, United States
The robustness of probabilistic versus deterministic DTI tractography in characterization of skeletal muscle structure is not yet established. We investigated the sensitivity to turning angle when probabilistic and deterministic methods were used to estimate fascicle lengths and fractional anisotropy in the arm’s biceps muscle (n=8). Results produced with deterministic methods were highly sensitive to the turning angle, but those produced with probabilistic methods were not. Furthermore, the recommended angle in probabilistic methods yielded findings consistent with ground truth measurements, while the turning angle in deterministic methods needed to be altered from the recommended value to achieve similar results.
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