Developing a robust quantitative diffusion MRI protocol for longitudinal assessment of neurodegenerative disorders
Amritha Nayak1,2, Diana Bharucha-Goebel3,4, M.Okan Irfanoglu2, Gilberto Averion3, Dimah Saade3, Carsten Bönnemann3, and Carlo Pierpaoli2
1Henry Jackson Foundation for advancement in Military Medicine Inc, Rockville, MD, United States, 2QMI, NIBIB, National Institutes of Health, Bethesda, MD, United States, 3NNDCS, NINDS, National Institutes of Health, Bethesda, MD, United States, 4Children's National Hospital, Division of Neurology, Washington DC, DC, United States
In this work, we have developed a quantitative diffusion MRI (dMRI) pipeline, to include acquisition, processing, and analysis, robust enough to evaluate the evolution of a neurodegenerative disease in each individual patient.
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