Abstract #1729

Developing a robust quantitative diffusion MRI protocol for longitudinal assessment of neurodegenerative disorders

Amritha Nayak^1,2, Diana Bharucha-Goebel^3,4, M.Okan Irfanoglu², Gilberto Averion³, Dimah Saade³, Carsten Bönnemann³, and Carlo Pierpaoli²

¹Henry Jackson Foundation for advancement in Military Medicine Inc, Rockville, MD, United States, ²QMI, NIBIB, National Institutes of Health, Bethesda, MD, United States, ³NNDCS, NINDS, National Institutes of Health, Bethesda, MD, United States, ⁴Children's National Hospital, Division of Neurology, Washington DC, DC, United States

Synopsis

In this work, we have developed a quantitative diffusion MRI (dMRI) pipeline, to include acquisition, processing, and analysis, robust enough to evaluate the evolution of a neurodegenerative disease in each individual patient.

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