Abstract #1734

Comparison of Language Areas determined by Resting State and Task Based fMRI using healthy subjects HCP data.

Robert Pretorius¹, Stefan Sunaert^1,2,3, and Ahmed Radwan¹

¹Department of Imaging and pathology, Translational MRI, Leuven, Belgium, KU Leuven, Leuven, Belgium, ²Leuven Brain Institute, Department of Neurosciences, Leuven, Belgium, KU Leuven, Leuven, Belgium, ³Department of Radiology, University Hospitals Leuven, Leuven, Belgium, University Hospital Leuven, Leuven, Belgium

Synopsis

Adding to the literature of resting state fMRI (rsfMRI) in preoperative planning, we investigated the similarity of a task based fMRI (tbfMRI) language protocol to a pan-language functional connectivity map in 10 healthy subjects. When comparing the whole brain there is relatively low Jaccard and Sorensen-Dice similarity between rsfMRI and tbfMRI language activity, however when looking at separate cortical anatomical regions the language areas are among those having the highest similarity. Additionally, there is a significantly higher similarity in the left IFG pars triangularis. This suggests that rsfMRI could be used reliably to determine Broca’s area in preoperative planning.

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