Plaque to Myocardium Ratio (PMR) based on T1-weighted MRI is an important quantitative biomarker to classify high-risk coronary plaque. However, it is calculated based on relative signal intensities, therefore, sensitive to variations in physiological and acquisition conditions. In this work, Bloch simulations were performed to explore the impact of heart rate, echo spacing, flip angle, and the number of readout segments on PMR. A computational model was further proposed to effectively reduce the acquisition-related PMR variations demonstrated in simulations and in vivo studies. The proposed method may potentially improve the precision of PMR and facilitate its comparison in longitudinal studies.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords