Abstract #1807

Free-Breathing Liver Fat Quantification using Radial Acquisition on a High-Performance 0.55T MRI System

Shu-Fu Shih^1,2, Sophia X. Cui³, Xiaodong Zhong³, Bilal Tasdelen⁴, Ecrin Yagiz⁴, Krishna S. Nayak⁴, and Holden H. Wu^1,2

¹Department of Radiological Sciences, University of California Los Angeles, Los Angeles, CA, United States, ²Department of Bioengineering, University of California Los Angeles, Los Angeles, CA, United States, ³Siemens Medical Solutions USA, Inc., Los Angeles, CA, United States, ⁴Ming Hsieh Department of Electrical and Computer Engineering, University of Southern California, Los Angeles, CA, United States

Synopsis

MRI proton-density fat fraction (PDFF) is used for non-invasive diagnosis of fatty liver disease, and has been validated at 1.5T and 3T field strengths. There is renewed interest in lower field strengths, such as 0.55T, because of potential advantages such as lower hardware/siting costs and a larger bore diameter. This study investigated PDFF quantification at 0.55T and validated PDFF quantification at 0.55T using Cartesian and Radial Dixon techniques in a reference phantom, and demonstrated the feasibility of in vivo free-breathing radial liver PDFF quantification in healthy subjects at 0.55T.

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