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Abstract #1831

Evidence for an intercollicular auditory push/pull mechanism revealed by BOLD fMRI

Frederico Severo1, Mafalda Valente1, and Noam Shemesh1
1Champalimaud Research, Champalimaud Centre for the Unknown, Lisboa, Portugal


The role of the rodent inferior colliculus (IC) in binaural integration is of great interest especially for sound localization and processing of interaural level difference (ILD). Yet, many IC underlying mechanisms remain unclear. Here, we find evidence for a push/pull mechanism in IC, with contralateral (positive BOLD) activity exerting dominance over ipsilateral (negative BOLD) activity, possibly as means of a sound localization/lateralization.

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