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Abstract #1835

MRI Measures of Non-atherosclerotic Brain Arterial Remodeling in a Population-based Study

Xinwei Zhou1, Melissa Caughey2, Arther Du3, Shang Zhou1, Yi-Pei Liu1, Shatorupa Ghosh2, Bruce Wasserman 1,4, and Ye Qiao1
1Radiology, Johns Hopkins University, Baltimore, MD, United States, 2Joint Department of Biomedical Engineering, University of North Carolina & North Carolina State University, Raleigh, NC, United States, 3Gilman School, Baltimore, MD, United States, 4Radiology, University of Maryland School of Medicine, Balitimore, MD, United States


We have reported reliable MRI measures of non-atherosclerotic brain arterial remodeling (NABAR), as assessed by outward and tortuous remodeling of the large intracranial arteries in older individuals. This will allow us to elucidate the predictors of prevalent and progressing NABAR, and its correlations with brain hypoperfusion and cognition function in an older community-based population.

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