In this study, we evaluate the test-retest repeatability of the recently developed multi-compartment relaxometry method for myelin water imaging (MCR-MWI). Cross-protocol repeatability is also studied using 3 GRE protocols with different echo spacing and TR. Good cross-session and cross-protocol repeatability is observed for MCR-MWI. Additionally, tissue parameters along 8 major white matter bundles are studied, and myelin water fraction is the most robust tissue parameter across various protocol settings.
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