Independent component analysis of rsfMRI data in pedophilic disorder: A Swedish case control study
Linnéa Andersson1, Christoffer Rahm2, Benny Liberg2, Maria Ljungberg1,3, and Isabella M. Björkman-Burtscher4,5
1Department of Medical Physics and Biomedical Engineering, Sahlgrenska University Hospital, Gothenburg, Sweden, 2Department of Internal Medicine, Karolinska Institute, Stockholm, Sweden, 3Department of Medical Radiation Sciences, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden, 4Department of Radiology, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden, 5Department of Radiology, Sahlgrenska University Hospital, Gothenburg, Sweden
Fifty percent of all child sexual abuse (CSA) perpetrators are individuals with pedophilic disorder. The neural underpinnings of pedophilic disorder are unknown. We conducted a case-control study aiming to investigate functional connectivity alterations using independent component analysis on resting state fMRI data in search of biomarkers that can be used for preventing CSA. The results suggest there are functional connectivity alterations in several resting state networks in individuals with pedophilic disorder.
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