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Abstract #2095

Brainstem 7T 1H-MRS: comparison between single-channel (1Tx32Rx) and parallel transmit (8Tx32Rx) coils

Carina Graf1, Belinda Ding1, Catarina Rua1,2, and Christopher T Rodgers1
1Wolfson Brain Imaging Centre, University of Cambridge, Cambridge, United Kingdom, 2Invicro LLC, A Konica Minolta Company, London, United Kingdom


7T MRS offers increased SNR and peak separation. Many Siemens 7T sites have both 1Tx32Rx and 8Tx32Rx head coils. Workflow is similar when using the TrueForm/CP+ mode. We compared MP2RAGE and semiLASER 1H-MRS in brainstem in healthy volunteers to identify a preferred coil for future studies.

Results: voxelplacement, linewidth, and concentrations were not significantly different. SNRNAA increased 27% and CRLBs for Gln, GABA & GSH trended to be lower for the 8Tx coil.

This encourages regular use of the 8Tx32Rx coil for brainstem 1H-MRS and facilitates method development by allowing full pTx sequences to be added on to scheduled examinations.

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