7T MRS offers increased SNR and peak separation. Many Siemens 7T sites have both 1Tx32Rx and 8Tx32Rx head coils. Workflow is similar when using the TrueForm/CP+ mode. We compared MP2RAGE and semiLASER 1H-MRS in brainstem in healthy volunteers to identify a preferred coil for future studies.
Results: voxelplacement, linewidth, and concentrations were not significantly different. SNRNAA increased 27% and CRLBs for Gln, GABA & GSH trended to be lower for the 8Tx coil.
This encourages regular use of the 8Tx32Rx coil for brainstem 1H-MRS and facilitates method development by allowing full pTx sequences to be added on to scheduled examinations.