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Abstract #2113

Combining the benefits of 3D acquisitions and spiral readouts in VASO fMRI

Alejandro Monreal1, Ruoyun Emily Ma1, Renzo Huber1, Denizhan Kurban1, Nicolas Boulant2, and Benedikt A Poser1
1Maastricht University, Maastricht, Netherlands, 2CEA NeuroSpin, Gif-sur-Yvette, France


VASO fMRI can provide beneficial localization specificity and quantifiability compared to the commonly used BOLD contrast. Previous work has also shown the benefits of using spiral readouts compared to Cartesian.

In this work, we explore the benefits of 3D stack of spirals readouts and compare it with the current state of the art 3D EPI readouts for VASO fMRI. The sequence implementation is done using Pulseq, images were reconstructed using gpuNUFFT; functional analysis with an openly available pipeline. We find that a tSNR efficiency improvement of a factor of 2.5 over EPI is achieved using the proposed spiral implementation.

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