Multiband acquisition can improve the temporal resolution of task-based fMRI at the cost of increased noise and artifacts. The optimal multiband acceleration depends on the task being studied, specific imaging protocol, and hardware involved. In the current work, multiband acceleration factors of 4, 5, and 6 were compared for a rhyming-task fMRI study using a 32-channel head coil on a compact 3T scanner with high-performance gradients. Multiband factors of 4 and 6 provided significant improvement over no acceleration, whereas a multiband factor of 5 was inconsistent and did not provide a significant improvement in half of the volunteer cohort.
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