Odor-identification is thought to be subserved by a distributed brain network that includes both the medial and inferior temporal lobes, still, its neural substrate remains poorly understood. Odor identification deficits are one of the hallmark symptoms of early Alzheimer’s disease (AD). Here, we propose the development of an oddball olfactory fMRI paradigm to establish the neural basis of odor-identification in healthy subjects. This task may provide a basis for establishing relationships between olfactory deficits, neurodegeneration, and memory impairment for current AD research.
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