In addition to focal spot localization for non-ablative transcranial ultrasound therapies, MR acoustic radiation force imaging (MR-ARFI) has the potential to estimate the acoustic intensity delivered to the target. However, variability in tissue stiffness and viscosity precludes accurate estimates of acoustic intensity from MR-ARFI displacements alone. We demonstrate that multifrequency MRE can be used to characterize a medium’s viscoelastic response to focused ultrasound, improving estimates of acoustic intensity and enabling safer, more effective treatments.
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