Mesoscopic fMRI with CBV-sensitive VASO can be a valuable tool for research questions on affected neural processing in patients suffering from neurological diseases. However, its applicability in patient populations remains unclear and is challenged by multiple methodological constraints. Here, we seek to use finger tapping tasks in hand dystonia patients to map affected topographical and laminar fMRI features. Specifically, we described the input-dominated laminar input-output circuits in the primary motor system as well as the ‘scrambled’ finger representations in the somatosensory areas. We built and validated an acquisition and analyses setup for laminar and columnar mapping in patient populations.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords