Abstract #2193

Laminar and columnar functional organization of human area MT using VASO at 7T

Alessandra Pizzuti^1,2, Renzo Huber¹, Omer Faruk Gulban^1,2, Amaia Benitez-Andonegui^1,3, Judith Peters¹, and Rainer Goebel^1,2

¹Department of Cognitive Neuroscience, Faculty of Psychology and Neuroscience, Maastricht University, Maastricht, Netherlands, ²Brain Innovation, Maastricht, Netherlands, ³National Institutes of Mental Health, MEG Core Facility, Bethesda, MD, United States

Synopsis

We investigate the feasibility of using CBV-sensitive VASO fMRI at ultra-high field to study the selective columnar organization to axes of motion stimuli in human area MT.

For 5 subjects we found:

BOLD and VASO both reveal characteristic tuning curves for axes of motion.
VASO is more specific and less sensitive than BOLD.
VASO layer profiles are less distorted by superficial veins than BOLD.
Columnar analysis is feasible using VASO.

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