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Abstract #2193

Laminar and columnar functional organization of human area MT using VASO at 7T

Alessandra Pizzuti1,2, Renzo Huber1, Omer Faruk Gulban1,2, Amaia Benitez-Andonegui1,3, Judith Peters1, and Rainer Goebel1,2
1Department of Cognitive Neuroscience, Faculty of Psychology and Neuroscience, Maastricht University, Maastricht, Netherlands, 2Brain Innovation, Maastricht, Netherlands, 3National Institutes of Mental Health, MEG Core Facility, Bethesda, MD, United States


We investigate the feasibility of using CBV-sensitive VASO fMRI at ultra-high field to study the selective columnar organization to axes of motion stimuli in human area MT.

For 5 subjects we found:

  • BOLD and VASO both reveal characteristic tuning curves for axes of motion.
  • VASO is more specific and less sensitive than BOLD.
  • VASO layer profiles are less distorted by superficial veins than BOLD.
  • Columnar analysis is feasible using VASO.

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