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Abstract #2217

On-board pseudo-MRI guidance for prostate radiotherapy on a conventional X-ray guided LINAC

Wendy Harris1, Ergys Subashi1, Victoria Yu1, Eric Aliotta1, Ricardo Otazo1, and Laura Cervino1
1Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY, United States


Current target localization for prostate radiotherapy on a conventional LINAC consists of acquiring a cone-bean CT (CBCT) image and matching it to implanted fiducial markers inside the prostate due to poor soft-tissue contrast of CBCT. MRI provides better soft tissue contrast and no ionization radiation, but there are very few MR-LINACs, and conventional LINACs with x-ray imaging capabilities are much more ubiquitous. This study proposes to use prior MRI acquisitions, PCA motion modeling, and on-board CBCT from a conventional LINAC to obtain on-board pseudo-MRI for target localization in prostate radiotherapy.

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