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Abstract #2307

Repeatability of Cartilage T2 relaxation times measures at 3T and 7T using quantitative double-echo in steady-state

Jessica Lauren Asay1, Anthony Andrea Gatti1, Arjun Divyang Desai1,2, Akshay Chaudhari1,3, Valentina Mazzoli1, Feliks Kogan1, and Garry Evan Gold1,4,5
1Radiology, Stanford University School of Medicine, Stanford, CA, United States, 2Electrical Engineering, Stanford University, Stanford, CA, United States, 3Biomedical Data Science, Stanford University School of Medicine, Stanford, CA, United States, 4Orthopaedic Surgery, Stanford University School of Medicine, Stanford, CA, United States, 5Bioengineering, Stanford University, Stanford, CA, United States

Synopsis

Quantitative MRI can be used to track subtle cartilage microstructure changes within a subject, which could be helpful in the early detection, treatment, and prevention of osteoarthritis. Increased field strength may offer higher resolution for detecting these changes. This study demonstrated the repeatability of mean T2 relaxation times measured at 3T and 7T. Full thickness cartilage T2 relaxation times at 3T and 7T had excellent ICCs, with CVs at 3T generally lower than 7T. This study suggests 3T and 7T measures are repeatable and can be used in longitudinal studies of cartilage changes.

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