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Abstract #2433

Accelerated Quantitative 3D UTE-Cones Imaging using Compressed Sensing

Jiyo S Athertya1, Ya-Jun Ma1, Amir Masoud Afsahi1, Alicia Ji1, Eric Y Chang1,2, Jiang Du1, and Hyungseok Jang1
1Radiology, University of California San Diego, San Diego, CA, United States, 2Radiology Service, VA San Diego Healthcare System, San Diego, CA, United States


Quantitative ultrashort echo time (qUTE) imaging suffers from long acquisition time due to multiple acquisitions required for parameter estimation. In this study, feasibility of accelerated qUTE Cones imaging with compressed sensing (CS) reconstruction is investigated for fast variable flip angle UTE-T1 mapping, adiabatic UTE-T mapping, and UTE quantitative magnetization transfer (MT) modelling of macromolecular fraction (MMF). We explored these biomarkers for qUTE-Cones imaging of in vivo human knee joints at various undersampling rates. The performance of CS-reconstruction and parameter mapping was evaluated in tendons, ligaments, menisci, and cartilage.

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