Abstract #2495

Quantitative evaluation of renal injury in the early chronic kidney disease with quantitative susceptibility mapping

Shan Jiayuan¹, Zhang Jinggang¹, Chen Jie¹, Xing Wei¹, Wang Yishi², and Zhang Jilei³

¹Third Affiliated Hospital of Soochow University, Changzhou, China, China, ²Philips Healthcare, Beijing, China, ³Philips Healthcare, Shanghai, China

Synopsis

To explore the value of quantitative susceptibility mapping (QSM) in evaluating renal injury in patients with chronic kidney disease (CKD). 40 CKD patients were included in the study to evaluate the potential clinical value of QSM. We found that with the progress of CKD staging, renal medulla susceptibility values decreased significantly. Susceptibility value of the medulla was highly correlated with estimated glomerular filtration rate (eGFR). QSM could serve as a quantitative biomarker to assess the renal injury of early CKD.

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