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Abstract #2506

Value of diffusion and intravoxel incoherent motion virtual MR elastography in differentiating benign and malignant focal liver lesions

Yuelang Zhang1, Xiang Li1, Chenxia Li1, Ting Cui1, Jinhan Wang1, Shuo Xing2, Xianjun Li1, and Jian Yang1
1the First Affiliated Hospital of Xi’an Jiaotong University, xi'an, China, 2Xi’an Jiaotong University, xi'an, China


Diffusion and IVIM virtual MR elastography (dMRE) provides quantitative estimates of tissue stiffness without using mechanical vibrations. It rarely applied to identify focal liver lesions (FLL). This retrospective study included 21 subjects (11 malignant lesions and 10 benign lesions). DWI were obtained to calculating dMRE. The kPa values of malignant FLLs (7.93 ± 2.37) was significantly higher than that of benign FLLs (-0.28±5.37) (P < 0.01). ROC showed an AUC of 0.93 for dMRE in differentiating maglinant FLLs and benign FLLs. The sensitivity and specificity were 91% and 90%, respectively. Malignant lesions could be distinguished from benign FLLs by dMRE.

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