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Abstract #2542

Measurement of gastric emptying with dynamic 3D DMI using a deuterium body array at 7 T

Ayhan Gursan1, Arjan D. Hendriks1, Dimitri Welting1, Dennis W.J. Klomp1, and Jeanine J. Prompers1
1Department of Radiology, University Medical Center Utrecht, Utrecht, Netherlands


Gastric emptying abnormalities are frequently observed in diabetes patients. Here we explored whether dynamic 3D DMI could be a radiation-free alternative for scintigraphy to measure the gastric emptying rate. One volunteer was scanned after oral intake of deuterated glucose and proximal and distal gastric emptying was monitored. The distribution of the glucose load in the proximal and distal parts of the stomach and the rate of gastric emptying agreed well with scintigraphy results. DMI has potential to investigate gastric emptying abnormalities in patients with diabetes, while at the same time providing information on glucose uptake and metabolism in the liver.

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