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Abstract #2576

Quantitative susceptibility mapping in the dynamic evaluation of renal ischemia-reperfusion injury in rabbits: a feasibility study

Kai Luo1, Jie Chen1, Jinggang Zhang1, and Weiqiang Dou2
1Third Affiliated Hospital of Soochow University, changzhou, China, 2MR Research China, GE Healthcare, Shanghai, China

Synopsis

The purpose was to explore whether quantitative susceptibility mapping (QSM) can assess the dynamic process of renal ischemia-reperfusion injury (IRI) in rabbits. We found that the magnetic susceptibility values of the outer medulla were statistically significant among the IRI group. Additionally, the magnetic susceptibility values of the outer medulla was highly correlated with the pathological score of renal injury. With these findings, QSM could serve as a quantitative biomarker to assess the dynamic changes of the outer medulla in the early stage of renal IRI.

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