Solving T2-blurring: Joint Optimization of Flip Angle Design and DenseNet Parameters for Reduced T2 Blurring in TSE Sequences
Hoai Nam Dang1, Jonathan Endres1, Felix Glang2, Simon Weinmüller1, Alexander Loktyushin2, Klaus Scheffler2, Arnd Doerfler1, Andreas Maier3, and Moritz Zaiss1,2
1Department of Neuroradiology, University Clinic Erlangen, Friedrich-Alexander University Erlangen-Nürnberg (FAU), Erlangen, Germany, 2Magnetic Resonance Center, Max-Planck-Institute for Biological Cybernetics, Tübingen, Germany, 3Department of Computer Science, Friedrich-Alexander University Erlangen-Nürnberg (FAU), Erlangen, Germany
We propose an end-to-end optimization approach to reduce T2 blurring in single-shot TSE sequences, by performing a joint optimization of Flip Angle Design and DenseNet parameters using he original transverse magnetization image at a certain TE as target. Our approach generalizes well to in vivo measurements at 3T, revealing enhanced white and grey matter contrast and fine structures in human brain.
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