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Abstract #2609

Hybrid supervised and self-supervised deep learning for quantitative mapping from weighted images using low-resolution labels

Shihan Qiu1,2, Anthony G. Christodoulou1,2, Yibin Xie1, and Debiao Li1,2
1Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States, 2Department of Bioengineering, UCLA, Los Angeles, CA, United States


Deep learning methods have been developed to estimate quantitative maps from conventional weighted images, which has the potential to improve the availability and clinical impact of quantitative MRI. However, high-resolution labels required for network training are not commonly available in practice. In this work, a hybrid supervised and physics-informed self-supervised loss function was proposed to train parameter estimation networks when only limited low-resolution labels are accessible. By taking advantage of high-resolution information from the input weighted images, the proposed method generated sharp quantitative maps and had improved performance over the supervised training method purely relying on the low-resolution labels.

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