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Abstract #2657

Correlation of vessel size and cerebral blood volume measurements in glioma genetic subtypes

Fatemeh Arzanforoosh1, Sebastian R. Van Der Voort1,2, Fatih Incekara1,3, Arnaud J. P. Vincent 3, Martin Van den Bent2,3, Marion Smits1,2, and Esther A.H. Warnert1,2
1Department of Radiology & Nuclear Medicine, Erasmus MC, Rotterdam, Netherlands, 2Erasmus MC Cancer Institute, Erasmus MC, Rotterdam, Netherlands, 3Department of Neurology, Erasmus MC, Rotterdam, Netherlands


Deep insight about tumor microvasculature is important for diagnosis and prognosis of glioma patients. Relative Cerebral Blood Volume (rCBV) and vessel size are two parameters, derived from perfusion MRI, used for evaluation of tumor microvasculature in glioma. In this study, we investigated the clinical value of both rCBV and vessel size and their correlation for three subgroups of glioma based on the recent 2021 World Health Organization (WHO) classification scheme. The result showed that neither rCBV nor vessel size differed significantly between glioma subtypes, though correlation of these two parameters sheds light on the microvasculature characteristics of each subgroup.

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