Abstract #2762
Portal Venous 4D Flow MRI in Obese Patients without Known Liver Disease Undergoing Weight Loss Surgery
Alma Spahic1, Grant Steven Roberts1, Tanya Wolfson2, David T Harris3, Nikolaos T Panagiotopoulos3,4, Alejandro Roldán-Alzate3,5,6, Kevin M Johnson1,3, Oliver T Wieben1,3, Claude B Sirlin7, Scott B Reeder1,3,5,6,8, and Thekla Helene Oechtering3,4
1Medical Physics, University of Wisconsin- Madison, Madison, WI, United States, 2Computational and Applied Statistics Laboratory, University of California San Diego, La Jolla, CA, United States, 3Radiology, University of Wisconsin- Madison, Madison, WI, United States, 4Radiology and Nuclear Medicine, Universität zu Lübeck, Lübeck, Germany, 5Mechanical Engineering, University of Wisconsin- Madison, Madison, WI, United States, 6Biomedical Engineering, University of Wisconsin- Madison, Madison, WI, United States, 7Radiology, University of California San Diego, San Diego, CA, United States, 8Emergency Medicine, University of Wisconsin- Madison, Madison, WI, United States
Synopsis
4D flow MRI of the portal vein has the potential to provide diagnostic value for detecting and staging certain liver diseases. To date, it is unknown whether weight loss influences portal flow in obese patients. We aimed to investigate the effect of weight loss on portal flow rate measured by non-contrast 4D flow MRI in obese patients undergoing weight loss surgery. Preliminary data of this ongoing study detected no statistically significant change in the mean volumetric portal flow rate in subjects during 2-6 months of weight loss. However, portal flow rate normalized to body weight or BMI increased significantly.
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