Abstract #2762

Portal Venous 4D Flow MRI in Obese Patients without Known Liver Disease Undergoing Weight Loss Surgery

Alma Spahic¹, Grant Steven Roberts¹, Tanya Wolfson², David T Harris³, Nikolaos T Panagiotopoulos^3,4, Alejandro Roldán-Alzate^3,5,6, Kevin M Johnson^1,3, Oliver T Wieben^1,3, Claude B Sirlin⁷, Scott B Reeder^1,3,5,6,8, and Thekla Helene Oechtering^3,4

¹Medical Physics, University of Wisconsin- Madison, Madison, WI, United States, ²Computational and Applied Statistics Laboratory, University of California San Diego, La Jolla, CA, United States, ³Radiology, University of Wisconsin- Madison, Madison, WI, United States, ⁴Radiology and Nuclear Medicine, Universität zu Lübeck, Lübeck, Germany, ⁵Mechanical Engineering, University of Wisconsin- Madison, Madison, WI, United States, ⁶Biomedical Engineering, University of Wisconsin- Madison, Madison, WI, United States, ⁷Radiology, University of California San Diego, San Diego, CA, United States, ⁸Emergency Medicine, University of Wisconsin- Madison, Madison, WI, United States

Synopsis

4D flow MRI of the portal vein has the potential to provide diagnostic value for detecting and staging certain liver diseases. To date, it is unknown whether weight loss influences portal flow in obese patients. We aimed to investigate the effect of weight loss on portal flow rate measured by non-contrast 4D flow MRI in obese patients undergoing weight loss surgery. Preliminary data of this ongoing study detected no statistically significant change in the mean volumetric portal flow rate in subjects during 2-6 months of weight loss. However, portal flow rate normalized to body weight or BMI increased significantly.

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