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Abstract #2795

Test-retest and inter-vendor variability of brain segmentation using 3D synthetic MRI in volunteers at 3T

Maarten Naeyaert1, Tim Vanderhasselt1, and Hubert Raeymaekers1
1Radiology, Universitair Ziekenhuis Brussel, Brussels, Belgium


Six volunteers were scanned two times on two different 3T scanners (GE, Philips) using the 3D-QALAS sequence. The intracranial and brain parenchymal volume and myelin content were determined and the brain segmented in cerebrospinal fluid and white and grey matter using synthetic MRI. Bland-Altman plots, Dice coefficient and coefficient of variation indicate that the test-retest variability is very small, but there is an inter-vendor bias for CSF, GM and WM. MyC, BPV and ICV have only a very limited inter-vendor bias. At least for GM and BPV, the expected inter-scanner variation, besides the bias, is below the clinically relevant threshold.

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