For imaging small-sized organs like the prostate, reduced-field-of-view (rFOV) technique is useful for shortening scan time, increasing resolution and reducing artifacts caused by field inhomogeneity and motion. Herein on a 3T clinical scanner, rFOV CEST was obtained using an off-resonance saturation preparation (seconds long), followed by readouts at the crossing section of a 90 deg excitation slab and a 180 deg refocus slab that had an angle in between. For saturation powers of 0.7 uT and 2 uT, CEST contrast maps and quantitative curves suggested the rFOV-CEST outperformed the Traditional-FOV acquisitions, which has potential for prostate CEST imaging at 3T.
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