Meeting Banner
Abstract #2817

Assessing intrinsic parallel diffusivity changes in pediatric subjects acquired with NODDI.

Antonio Napolitano1, Martina Lucignani1, Chiara Parrillo1, Maria Camilla Rossi Espagnet1, Daniela Longo1, and Lorenzo Figà Talamanca1
1Bambino Gesù Children's Hospital, Rome, Italy


Investigating optimal NODDI intrinsic diffusivity d|| values in the first years of life would provide accurate diffusion properties estimation. We aimed to investigate d|| for 1-36 months range. Diffusion data from 265 baby Human Connectome Project subjects were processed and used for NODDI model fitting with MDT tool. Among different d|| tested, optimal value was chosen according to maximum LogLikelihood maps and investigated as a function of age. Infants exhibit optimal d|| values of 1.95 µm2 ms-1, where d|| decreases for increasing age. Based on our results, 1.7 µm2 ms-1 represent a suboptimal assumption in the case of infant population.

This abstract and the presentation materials are available to members only; a login is required.

Join Here