Abstract #2887

Assessment of Lumbar Nerve Root Changes in Disc Herniation Using Ultrashort Echo Time Magnetization Transfer (UTE-MT) Imaging

Jin Liu¹, Jia-Xin Feng¹, Jian-Wei Liao¹, Wei Li¹, Xiao-Jun Chen¹, Lin Yao¹, Pan-Hui Huang¹, Long Qian², Ya-Jun Ma³, and Shao-Lin Li¹

¹Department of Radiology, The Fifth Affiliated Hospital of Sun Yat-Sen University, Zhuhai, China, ²MR Research, GE Healthcare, Beijing, China, ³Department of Radiology, University of California San Diego, San Diego, CA, United States

Synopsis

Ultrashort echo time magnetization transfer (UTE-MT) imaging can quantify macromolecular content changes in tissues. This study aims to investigate the feasibility of UTE-MT ratio (UTE-MTR) in assessment of lumbar nerve root changes due to disc herniation. T₂ mapping and diffusion tensor imaging (DTI) were also employed for comparison. Our results demonstrated that the UTE-MTR is able to detect nerve root changes due to disc herniation and it has a better performance than T₂ mapping and DTI imaging in differentiation of disc herniation and non-disc herniation.

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