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Abstract #2901

Phosphorus MR Spectroscopy of Healthy Human Spleen

Jan Weis1, Maysam Jafar2, and Per Liss3
1Department of Medical Physics, Uppsala University Hospital, Uppsala, Sweden, 2Philips Nordic, Stockholm, Sweden, 3Department of Surgical Sciences, Section of Radiology, Uppsala University Hospital, Uppsala, Sweden


Phosphorous spectra of healthy spleen are useful for studies of splenic malignancies and benign causes of splenomegaly. The main challenge is the relatively small size of the normal spleen and the large distance between human spleen and surface coil. The purpose of this study was to investigate whether it is possible to acquire phosphorous spectra of healthy spleen using single-voxel ISIS sequence on a 3T scanner. We demonstrate that the proposed spectroscopy of human spleen is feasible in a clinically acceptable acquisition time and that transmitter excitation profile and chemical shift displacement errors need to be taken into consideration

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