Abstract #2976

The Diagnostic Value of Quantitative Analysis of Synthetic MRI, ASL and DWI in Grading Gliomas as Compared to Conventional MRI: A Preliminary Study

Xin Ge^1,2, Xueying Huang², Aijun Wang², Kai Zhu², Xiaocheng Wei³, Min Li⁴, Ying Shen^1,2, Wenxiao Liu^1,2, Peng Yong^1,2, Ruirui Lv^1,2, Xuhong Yang^1,2, and Xiaodong Wang²

¹Ningxia Medical University, Yinchuan, China, ²General Hospital of Ningxia Medical University, Yinchuan, China, ³GE Healthcare, MR Research, Beijing, China, Beijing, China, ⁴GE Healthcare, MR Enhancement Application, Beijing, China, Beijing, China

Synopsis

This work sought to investigate the performance of synthetic MRI, ASL and DWI in differentiating LGGs from HGGs as compared to conventional MRI. It was concluded that the T1 and PD from synthetic MRI can be used as novel quantitative imaging biomarkers for grading gliomas. Combining T1, PD, CBF and ADC may explore as an effective strategy to improve the ability for discriminating gliomas grade, and outperformed conventional approaches.

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