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Abstract #2976

The Diagnostic Value of Quantitative Analysis of Synthetic MRI, ASL and DWI in Grading Gliomas as Compared to Conventional MRI: A Preliminary Study

Xin Ge1,2, Xueying Huang2, Aijun Wang2, Kai Zhu2, Xiaocheng Wei3, Min Li4, Ying Shen1,2, Wenxiao Liu1,2, Peng Yong1,2, Ruirui Lv1,2, Xuhong Yang1,2, and Xiaodong Wang2
1Ningxia Medical University, Yinchuan, China, 2General Hospital of Ningxia Medical University, Yinchuan, China, 3GE Healthcare, MR Research, Beijing, China, Beijing, China, 4GE Healthcare, MR Enhancement Application, Beijing, China, Beijing, China

Synopsis

This work sought to investigate the performance of synthetic MRI, ASL and DWI in differentiating LGGs from HGGs as compared to conventional MRI. It was concluded that the T1 and PD from synthetic MRI can be used as novel quantitative imaging biomarkers for grading gliomas. Combining T1, PD, CBF and ADC may explore as an effective strategy to improve the ability for discriminating gliomas grade, and outperformed conventional approaches.

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