Abstract #3020

Performance of single-shot echo-planar imaging DTI in rat sciatic nerve compared with readout-segmented echo-planar imaging

Yueyao Chen¹, Zhongxian Pan¹, Fanqi Meng¹, Zhujing Li¹, Jinyun Gao¹, Yuanming Hu¹, Yihao Guo², Qian Xu¹, Leyu Huang¹, and Hanqing Lv*¹

¹Department of Radiology, Shenzhen Traditional Chinese Medicine Hospital (The Fourth Clinical Medical College of Guangzhou University of Chinese Medicine), Shenzhen, China, ²MR Collaboration, Siemens Healthineers Ltd., Guangzhou, China

Synopsis

This study compared single-shot echo-planar imaging (SS-EPI) with readout-segmented echo-planar imaging (RS-EPI) diffusion tensor imaging (DTI) in vivo anesthetized rat sciatic nerve at 3T. The result showed that the image quality scores of SS-EPI were higher than those of RS-EPI in terms of the nerve morphology and homogeneity of the neuromuscular region. The coefficients of FA and RD obtained with SS-EPI were higher than those obtained with RS-EPI SS-EPI. This suggests that in rat sciatic nerve DTI, SS-EPI showed higher image quality and offered more sensitive and stable parameters to detect the histopathological change in the rat sciatic nerve.

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