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Abstract #3042

Quantifying the Stiffness of Peritrigonal Terminal Zones in Preschool Children by Diffusion Imaging-based Virtual MRI Elastography

Na Zhang1, Xianjun Li1, Congcong Liu1, Yao Ge1, Yuying Feng1, Pengxuan Bai1, Miaomiao Wang1, and Jian Yang1
1Department of Radiology, The First Affiliated Hospital of Xi’an Jiaotong University, Xi'an, China


The high signal intensity on T2-weighted images in terminal zones (TZ) mainly associated with lower maturational degree. We hypothesized that the stiffness in these regions may be different from typical developing children without TZ. Virtual stiffness of brain can be measured safely with virtual magnetic resonance elastography (vMRE). Therefore, this study tried to use vMRE to investigate differences between children with and without TZ. Results demonstrated that virtual stiffness of TZ was lower than controls, while higher than periventricular leukomalacia. These suggest that vMRE may provide additional information for evaluating brain maturation and injury.

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