Preterm infants are at high risk of adverse neurodevelopmental outcome. Therefore, it is necessary to find a tool to detect brain developmental abnormalities earlier. Diffusion kurtosis imaging (DKI) is considered as a more accurate technology based on a kurtosis model accounting for the variation of Gaussian distribution caused by complex cellular environments in compare with diffusion tensor imaging. The mean kurtosis (MK) in posterior limbs of the internal capsule (PLIC), anterior limb of internal capsule (ALIC), the mean diffusion (MD) in parietal white matter (PWM) were found with good diagnostic performance for abnormal brain microstructural change.
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