Abstract #3094
Three-dimensional architecture and diffusion properties of the medial gastrocnemius muscle in human infants in vivo
Brian V. Y. Chow1,2, Bart Bolsterlee1,3, Catherine Morgan4, Caroline Rae1, David I. Warton5,6, Iona Novak4,7, Suzanne Davies1, Ann Lancaster1, Gordona C. Popovic5,8, Rodrigo R. N. Rizzo1,2, Claudia Y. Rizzo1, Maria Kyriagis9, Melissa Smith1, Erin Muling1, and Robert D. Herbert1,2
1Neuroscience Research Australia, Sydney, Australia, 2School of Medical Sciences, University of New South Wales, Sydney, Australia, 3Graduate School of Biomedical Engineering, University of New South Wales, Sydney, Australia, 4Cerebral Palsy Alliance Research Institute, The University of Sydney, Sydney, Australia, 5School of Mathematics and Statistics, University of New South Wales, Sydney, Australia, 6Evolution & Ecology Research Centre, University of New South Wales, Sydney, Australia, 7Faculty of Medicine and Health, The University of Sydney, Sydney, Australia, 8Stats Central, Mark Wainwright Analytical Centre, University of New South Wales, Sydney, Australia, 9Rehab2Kids, Sydney Children’s Hospital, Sydney, Australia
Synopsis
Diffusion tensor magnetic resonance imaging (DT-MRI) was used to investigate the three-dimensional architecture and diffusion properties of medial gastrocnemius muscles in living human infants aged 2-3 months. Mean muscle volume, physiological cross-sectional area and fascicle length in infants were 1.8%, 3.8% and 47.2% of values previously obtained in 8 adult muscles. Radial diffusivity in infant muscle was half that in adult muscle, presumably because infant muscle fibres have much smaller transverse dimensions.
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