Dynamic T2 mapping of human skeletal muscles via multiple overlapping-echo detachment planar imaging
Yang Qizhi1, Wang Xiaoyin2, Cai Shuhui1, He Hongjian2, Cai Congbo1, Wu Zhigang3, and Zhong Jianhui2,4
1Department of Electronic Science, School of Electronic Science and Engineering, Xiamen University, Xiamen, Fujian, China, 2Center for Brain Imaging Science and Technology, College of Biomedical Engineering and Instrumental Science, Zhejiang University, Hangzhou, Zhejiang, China, 3MSC Clinical & Technical Solutions, Philips Healthcare, Shenzhen, Guangdong, China, 4Department of Imaging Science, University of Rochester, Rochester, NY, United States
Magnetic resonance (MR) parametric mapping and MR dynamic imaging are both valuable clinical tools. Nevertheless, quantitative imaging and high time resolution usually cannot be achieved simultaneously with conventional dynamic MR imaging methods. Herein, the multiple overlapping-echo detachment imaging (MOLED) method with short echo time (TE), dubbed MOLED-short, is proposed to fetch the dynamic variation of T2 value on in vivo extremities with high temporal resolution (about 110 ms). The robustness of MOLED-short was demonstrated. MOLED-short can capture immediate T2 changes of muscles and may provide new insights into the metabolic responses of musculatures to human activities.
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