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Abstract #3139

Three-dimension Amide Proton Transfer Imaging for Predicting the Treatment Response of Nasopharyngeal Carcinoma

Wenguang Liu1, Yigang Pei1, Simin Xie1, Xiao Wang1, Yu Bai1, Gaofeng Zhou1, Weiyin Vivian Liu2, and Wenzheng Li1
1Department of Radiology, XiangYa Hospital, Central South University, Changsha, China, 2GE Healthcare, Beijing, China


To predict the treatment response for NPC patients is very important. This study aimed to explore the diagnostic performance of 3D APT imaging on predicting the treatment response of NPC patients. A total of 40 patients and 14 healthy volunteers were identified in this study. Result show that the APT and MT values have good and excellent intra- and inter-observer agreement. It is significant difference for MT values between residual and non-residual group. The result suggests that the pre-treatment MT values can be used to predict treatment response of NPC with chemoradiotherapy, and better than the APT and ADC value.

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