Monitoring the response to induction therapy of multiple myeloma by diffusion weighted and mDIXON Quant whole body imaging
Mengtian Sun1, Jingliang Cheng1, Cuiping Ren1, Jie Ma2, and Liangjie Lin3
1MRI, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, China, 2Hematology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, China, 3Philips Healthcare, Beijing, China
This study aims to investigate the value of whole-body DWIBS and mDIXON Quant imaging in monitoring the response to induction therapy of multiple myeloma focal lesions (FLs). Significant differences in the number of multiple myeloma focal lesions (FLs), the maximum diameter of FLs, ADC, FF, T2* values, ADC change rate, FF change rate and T2* change rate were observed between the deep remission group and the non-deep remission group. The FF change rate was the best discriminator of the deep remission.
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