Abstract #3146

Monitoring the response to induction therapy of multiple myeloma by diffusion weighted and mDIXON Quant whole body imaging

Mengtian Sun¹, Jingliang Cheng¹, Cuiping Ren¹, Jie Ma², and Liangjie Lin³

¹MRI, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, China, ²Hematology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, China, ³Philips Healthcare, Beijing, China

Synopsis

This study aims to investigate the value of whole-body DWIBS and mDIXON Quant imaging in monitoring the response to induction therapy of multiple myeloma focal lesions (FLs). Significant differences in the number of multiple myeloma focal lesions (FLs), the maximum diameter of FLs, ADC, FF, T2* values, ADC change rate, FF change rate and T2* change rate were observed between the deep remission group and the non-deep remission group. The FF change rate was the best discriminator of the deep remission.

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