The purpose of this study is to explore the feasibility of magnetic resonance imaging (MRI) 3D multi-echo-Dixon (ME-Dixon) and T2-corrected multi-echo single-voxel (HISTO) spectroscopy sequences to evaluate osteoporosis by comparison with quantitative computed tomography (QCT). The results show that the proton density fat fraction (PDFF) values of bone marrow measured by these two MRI methods have high and significantly negative correlation with bone mineral density (BMD) values measured by QCT at lumbar.
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