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Abstract #3171

Association between white matter hyperintensity and diabetes-related mild cognitive impairment

Yashi Nan1, Jian Zhang1, Jianming Ni2, and Silun Wang1
1Yiwei Medical Technology, Shenzhen, China, 2Department of Radiology, Wuxi No2. People’s Hospital, Affiliated Wuxi Clinical College of Nantong University, Wuxi, China


White matter hyperintensities (WMH) features may assist detecting diabetes-related MCI. We aimed to identify the correlations between WMH and MCI in T2D using brain magnetic resonance imaging. Fifty participants, matched for age, were included. Total and regional WMH volumes were calculated using automated segmentation approach. WMH patterns were compared between groups using a voxel-wise analysis. Results show that cognitive impairment was related to a higher prevalence of regional WMH. Subcortical WMH volumes in specific brain regions. The findings suggested that the presence of WMH in specific regions rather the WMH volumes appears to be correlated with the MCI in T2D.

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