White matter hyperintensities (WMH) features may assist detecting diabetes-related MCI. We aimed to identify the correlations between WMH and MCI in T2D using brain magnetic resonance imaging. Fifty participants, matched for age, were included. Total and regional WMH volumes were calculated using automated segmentation approach. WMH patterns were compared between groups using a voxel-wise analysis. Results show that cognitive impairment was related to a higher prevalence of regional WMH. Subcortical WMH volumes in specific brain regions. The findings suggested that the presence of WMH in specific regions rather the WMH volumes appears to be correlated with the MCI in T2D.
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